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There is bustling excitement growing around the health benefits of Lion’s Mane mushrooms. This unique medicinal mushroom has received far-reaching attention for its capacity to improve brain function, mental well-being, memory, and mood. These health benefits are not only supported by a growing body of scientific evidence but also countless first-hand experiences.

Lion’s Mane has captivated researchers studying treatments for illnesses such as Alzheimer’s, dementia, anxiety, depression, and other forms of cognitive dysfunction.

Other individuals use Lion’s Mane as a day-to-day ally for overcoming exhaustion, lack of focus, brain fog, and other stress related maladies exacerbated by our modern-day lifestyle.

For these reasons, Lion’s Mane has quickly become one of the most popular medicinal mushrooms on the market.

What is Lion's Mane Mushroom?

Lion’s Mane is a wood-loving mushroom native to Europe, Asia, and North America. It is scientifically known as Hericium erinaceus and is easily recognized by its white color, spherical shape, and hundreds of thin dangling tassel-like teeth.

Lion’s Mane is relatively rare in the wild but is cultivated worldwide. While it is an esteemed gourmet mushroom, it is most often found today as a health supplement.

How Does Lion’s Mane Work?

The cognitive benefits of Lion’s Mane are thanks to several unique compounds which support brain health. The most well-known are hericenones and erinacines.

These compounds are not only neuroprotective but also stimulate neurogenesis by promoting a compound called “Nerve-Growth-Factor”.²¹This compound directly promotes the growth of new neurons.

Hericenones and erinacines also help with the functioning of neural pathways. For example, they have also been shown to help against the build-up of amyloid plaque³, a compound linked to Alzheimer’s disease and Dementia. They also have been shown to promote the regeneration of the “myelin sheath”, which facilitates the fluidity and function of the neural pathways.²²

For this same reason, Lion’s Mane is also being studied in treating nerve damage and nervous system dysfunctions. A recent study has revealed another novel compound, N-de phenylethyl isohericerin (or simply NDPIH), which may also support cognitive health.²³

Lion’s Mane also contains specialized polysaccharides called beta-glucans. These are soluble fibers that have been shown to support immune function, digestive health, and have been rigorously studied for their use in cancer therapies.²⁴They are found within many different medicinal mushrooms, but every variety has unique beta-glucans. Certain grains also contain beta-glucans, but only the unique structure of the fungal beta-glucans (known as (1,3;1,6)-β-D-Glucans) have potent bioactivity.

What Mind and Mane Offers

Made With Real Fruiting Bodies: Mind and Mane products contain extracts made with 100% fruiting bodies. Many other brands you see at the store do not use mushroom fruiting bodies, but instead the white filamentous root-like structure of the fungi known as “mycelium”. Mycelium is cheaper to produce, but unfortunately for unsuspected consumers, it contains much fewer bioactive compounds²⁵ ²⁶. If a supplement does not mention using 100% fruiting bodies, it probably isn’t!

Potent 4:1 Extracts: Our extracts are made using state-of-the-art equipment at a 4:1 ratio. This means that 4 grams of dried Lion’s Mane mushrooms are utilized for every gram of our extract.

Research-Verified Dosage: For any medicine to be effective, it must be consumed at adequate dosages verified by clinical trials and other scientific research. This is about 3-5 grams of dried Lion’s Mane consumed daily. This is what our product offers, which is a strength at least 3x more potent than most competitors!

How To Consume Lion’s Mane

To reap the benefits of Lion’s Mane mushrooms, they should be consumed daily for an extended period. At least 2-3 weeks of daily consumption is often required before they become effective. While there may be some long-term health benefits, the effects have not been shown to last much longer beyond the time of utilization.

Like any medicine, Lion’s Mane is most effective when combined with a holistic health regime. This means incorporating a healthy diet, exercise, rest, and social activity into your lifestyle.

Other herbs, medications, and therapeutic practices recommended by health professionals may also be helpful in the treatment of both mild/serious conditions.

Likewise, restraining from activities with known health consequences is also essential for the treatment to be most effective.

Risks and Side Effects

Generally speaking, Lion’s Mane is considered an exceptionally safe mushroom with little to no side effects. Remember, this mushroom is also consumed as a gourmet edible in much larger quantities than the doses recommended as a health supplement.

This being said, much research is still required to confirm the long-term safety of Lion’s Mane. No studies have been conducted on the safety of Lion’s Mane for pregnant women, nor about possible interactions with other medications. For this reason, always consult a qualified health practitioner before consuming Lion’s Mane mushrooms.

Everyone has a unique biology influenced by their genes, diet, and life history. While most people do not suffer negative side effects from Lion’s Mane, others may be susceptible. Skin rashes, abdominal pain, and nausea have been reported from Lion’s Mane supplements in some clinical trials ²⁷ ²⁸, although the exact cause has not been confirmed. There is also anecdotal evidence that it may lower male libido and could even cause dysphoria.

If you suffer any negative side effects from consuming Lion’s Mane mushrooms, you should stop consuming them immediately.

Try It For Yourself

The best way to know if Lion’s Mane is a suitable supplement for you is to give it a try. Remember, for it to be effective, Lion’s Mane must be consumed daily at the proper dosage for at least four weeks. Most individuals will notice a significant increase in mood, memory, and brain function within the first 2-3 weeks. If you do not notice any significant improvement in your mood, memory, or brain function after four weeks, Lion’s Mane may not be for you.

We encourage you to further research all the potential benefits of Lion’s Mane. While there are countless products, think critically before purchasing any product which claims to contain Lion’s Mane.

Mind and Mane products are carefully crafted and aligned with the latest scientific research. They are effective, easy to take, and delicious. Not only are they a great way to reap the benefits of Lion’s Mane, but they also contain a dose of the legendary Reishi mushroom. This mushroom, known as the “herb of immortality”, has been used for thousands of years in Traditional Chinese Medicine and offers a whopping list of health benefits.

By mixing Lion’s Mane and Reishi, we have designed a well-rounded product designed to improve well-being, promote healthy aging, and help anyone overcome their day-to-day hurdles.

  1. Mori, K., Inatomi, S., Ouchi, K., Azumi, Y., & Tuchida, T. (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: A double‐blind placebo‐controlled clinical trial. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 23(3), 367-372.
  2. Saitsu, Y., Nishide, A., Kikushima, K., Shimizu, K., & Ohnuki, K. (2019). Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomedical Research, 40(4), 125-131.
  3. Mori, Koichiro, et al. “Effects of Hericium erinaceus on amyloid β (25-35) peptide-induced learning and memory deficits in mice.” Biomedical Research 32.1 (2011): 67-72.
  4. Ratto, D., Corana, F., Mannucci, B., Priori, E. C., Cobelli, F., Roda, E., … & Rossi, P. (2019). Hericium erinaceus improves recognition memory and induces hippocampal and cerebellar neurogenesis in frail mice during aging. Nutrients, 11(4), 715.
  5. Brandalise, Federico, et al. “Dietary supplementation of Hericium erinaceus increases mossy fiber-CA3 hippocampal neurotransmission and recognition memory in wild-type mice.” Evidence-Based Complementary and Alternative Medicine 2017 (2017).
  6. Zhang, J., An, S., Hu, W., Teng, M., Wang, X., Qu, Y., … & Wang, D. (2016). The neuroprotective properties of Hericium erinaceus in glutamate-damaged differentiated PC12 cells and an Alzheimer’s disease mouse model. International journal of molecular sciences, 17(11), 1810.
  7. Skubel, T., Budzyńska, J., Czarnota, J., Dobrzyński, M., Rybak, N., & Dudek, I. (2022). Therapeutic potential of Lion’s Mane (Hericium erinaceus) in neurological and cognitive disorders-a review of the literature. Journal of Education, Health and Sport, 12(9), 498-504.
  8. Nagano, M., Shimizu, K., Kondo, R., Hayashi, C., Sato, D., Kitagawa, K., & Ohnuki, K. (2010). Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomedical Research, 31(4), 231-237.
  9. Vigna, L., Morelli, F., Agnelli, G. M., Napolitano, F., Ratto, D., Occhinegro, A., … & Rossi, P. (2019). Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity: could circulating pro-BDNF and BDNF be potential biomarkers?. Evidence-Based Complementary and Alternative Medicine, 2019.
  10. Chong, P. S., Fung, M. L., Wong, K. H., & Lim, L. W. (2019). Therapeutic potential of Hericium erinaceus for depressive disorder. International journal of molecular sciences, 21(1), 163.
  11. Qin, M., Geng, Y., Lu, Z., Xu, H. Y., Shi, J. S., Xu, X., & Xu, Z. H. (2016). Anti-inflammatory effects of ethanol extract of lion’s mane medicinal mushroom, hericium erinaceus (agaricomycetes), in mice with ulcerativ colitis. International Journal of Medicinal Mushrooms, 18(3).
  12. Yang, Y., Zhao, C., Diao, M., Zhong, S., Sun, M., Sun, B., … & Zhang, T. (2018). The prebiotic activity of simulated gastric and intestinal digesta of polysaccharides from the Hericium erinaceus. Molecules, 23(12), 3158.
  13. Wang, X. Y., Yin, J. Y., Zhao, M. M., Liu, S. Y., Nie, S. P., & Xie, M. Y. (2018). Gastroprotective activity of polysaccharide from Hericium erinaceus against ethanol-induced gastric mucosal lesion and pylorus ligation-induced gastric ulcer, and its antioxidant activities. Carbohydrate polymers, 186, 100-109.
  14. Diling, C., Xin, Y., Chaoqun, Z., Jian, Y., Xiaocui, T., Jun, C., … & Yizhen, X. (2017). Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota. Oncotarget, 8(49), 85838.
  15. Sheng, X., Yan, J., Meng, Y., Kang, Y., Han, Z., Tai, G., … & Cheng, H. (2017). Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology. Food & Function, 8(3), 1020-1027.
  16. Kim, S. P., Moon, E., Nam, S. H., & Friedman, M. (2012). Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-induced liver damage and mortality by stimulation of innate immune cells. Journal of agricultural and food chemistry, 60(22), 5590-5596.
  17. Liu, Jianqing, et al. “Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.” Experimental and therapeutic medicine 9.2 (2015): 483-487.
  18. Komiya, Y., Nakamura, T., Ishii, M., Shimizu, K., Hiraki, E., Kawabata, F., … & Mizunoya, W. (2019). Increase in muscle endurance in mice by dietary Yamabushitake mushroom (Hericium erinaceus) possibly via activation of PPAR δ. Animal Science Journal, 90(6), 781-789.
  19. Li, G., Yu, K., Li, F., Xu, K., Li, J., He, S., … & Tan, G. (2014). Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers. Journal of ethnopharmacology, 153(2), 521-530.
  20. AM, Y. (2017). Anticancer potential of Hericium erinaceus extracts against particular human cancer cell lines. Microbial Biosystems, 2(1), 9-20.
  21. Kawagishi, Hirokazu, et al. “Hericenones C, D and E, stimulators of nerve growth factor (NGF)-synthesis, from the mushroom Hericium erinaceum.” Tetrahedron Letters 32.35 (1991): 4561-4564.
  22. Cheng, J. H., Tsai, C. L., Lien, Y. Y., Lee, M. S., & Sheu, S. C. (2016). High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity. BMC Complementary and Alternative Medicine, 16, 1-9.
  23. Martínez-Mármol, R., Chai, Y., Conroy, J. N., Khan, Z., Hong, S. M., Kim, S. B., … & Meunier, F. A. Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory. Journal of neurochemistry.
  24. Van Steenwijk, H. P., Bast, A., & De Boer, A. (2021). Immunomodulating effects of fungal beta-glucans: From traditional use to medicine. Nutrients, 13(4), 1333.
  25. Rogers, R. D. (2016) Mushrooms Vs. Mycelium: Choosing the Best Medicinal.
  26. NAMMEX (2017).  Redefining Medicinal Mushrooms.
  27. Li, I. C., Chang, H. H., Lin, C. H., Chen, W. P., Lu, T. H., Lee, L. Y., … & Lin, D. P. C. (2020). Prevention of early Alzheimer’s disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Frontiers in aging neuroscience, 12, 155.
  28. Mori 2008.
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